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Loaf of homemade blueberry bread with fresh blueberries on a wooden table

Blueberry Cream Cheese Bread

This Blueberry Cream Cheese Bread is a soft, tangy loaf filled with creamy goodness and bursting with fresh blueberries. Perfect for brunch or as a cozy treat!
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Prep Time 20 minutes
Cook Time 1 hour
Total Time 1 hour 15 minutes
Servings: 8 slices
Course: Breakfast, Brunch, Dessert
Cuisine: American
Calories: 250
Ingredients Method Notes

Ingredients
  

Dough Ingredients
  • 3 cups all-purpose flour, plus more for dusting
  • 1 teaspoon baking soda
  • 1/2 teaspoon salt
  • 1 cup granulated sugar
  • 1/2 cup unsalted butter, softened
  • 2 large eggs Room temperature for best mixing
  • 1 teaspoon vanilla extract
  • 1 cup sour cream
  • 1 cup fresh blueberries, plus more for topping Use fresh for best texture
Cream Cheese Filling
  • 8 ounces cream cheese, softened
  • 1/4 cup granulated sugar For filling
  • 1 large egg yolk
  • 1/2 teaspoon vanilla extract For filling
Crumble Topping (Optional)
  • 1/2 cup all-purpose flour
  • 1/4 cup granulated sugar For crumble
  • 1/4 cup packed light brown sugar
  • 1/4 teaspoon ground cinnamon
  • 1/4 cup cold unsalted butter, cut into small pieces

Method
 

Prepare Cream Cheese Filling
  1. Beat softened cream cheese with 1/4 cup sugar until smooth. Mix in the egg yolk and 1/2 teaspoon vanilla, then set aside.
Make Crumble (Optional)
  1. Whisk together 1/2 cup flour, 1/4 cup sugar, brown sugar, and cinnamon. Cut in cold butter until coarse crumbs form; set aside.
Prepare Batter
  1. Preheat the oven to 350°F (175°C). Grease and flour a 9x5-inch loaf pan.
  2. In a medium bowl, whisk together 3 cups flour, baking soda, and salt until blended.
  3. In a large bowl, cream 1 cup sugar with 1/2 cup softened butter until light and fluffy. Beat in the eggs, one at a time, then stir in 1 teaspoon vanilla.
  4. Gradually add dry ingredients to the wet, alternating with 1 cup sour cream, beginning and ending with dry. Mix just until combined.
  5. Gently fold in 1 cup fresh blueberries.
Assemble and Bake
  1. Pour half the batter into the prepared pan. Spoon the cream cheese filling down the center. Cover with remaining batter and smooth the top.
  2. Sprinkle crumble and extra blueberries on top if using.
  3. Bake for 55–65 minutes or until the top is golden and a skewer comes out clean.
  4. Let cool in the pan for 10–15 minutes, then transfer to a rack to cool completely before slicing.

Notes

Use fresh blueberries for best texture. Room-temperature eggs mix more evenly. Consider pairing with yogurt and granola for a complete brunch.